Search Clinical Trials in the European Union

Duration
Visits
Safety phase (I)
Intake methods
Benefits
Drugs
Locations
Clinical Specialty
761-780 of 936 trials

Bone Health: Cagrilintide Study

We are investigating how the amylin analogue Cagrilintide affects bone metabolism in participants. This study aims to learn more about its potential role in improving bone health.

Obesity in Post-Menopausal WomenSafety phase (I)EndocrinologyInternal Medicine

Rheumatoid Arthritis: F8IL10 Injection Study

We are exploring different doses of an injection for people with rheumatoid arthritis. The goal is to find out how well it works and its safety profile.

Rheumatoid Arthritis>2 yearsSafety phase (I)Rheumatology

Knee Osteoarthritis: SYN321 Injection Study

We are testing a new injection for people with knee osteoarthritis to see if it is safe and effective. The study compares different doses of SYN321 to a placebo to assess its impact on symptoms.

Knee Osteoarthritis≤3 monthsSafety phase (I)Efficacy phase (II)Investigational MedicinesInternal MedicineOrthopedics and Traumatology

Midgut Neuroendocrine Tumors: Lu177-Dotatate Treatment Schedule

We are studying whether giving Lu177-Dotatate every 16 weeks can lower serious side effects for patients with advanced midgut neuroendocrine tumors. This trial compares the new schedule to the standard treatment given every 8 weeks.

Small Intestine Neuroendocrine Tumor>2 yearsSafety phase (I)Efficacy phase (II)≤5 visitsNo PlaceboStandard MedicinesPartially RemoteGastroenterologyOncology

Small Cell Lung Cancer: MK-6070 and Ifinatamab Deruxtecan Study

We are studying the safety and effectiveness of MK-6070 combined with ifinatamab deruxtecan in people with advanced small cell lung cancer. This trial aims to find better treatment options for those whose cancer has returned or is hard to treat.

Small Cell Lung Cancer>2 yearsSafety phase (I)Efficacy phase (II)11-15 visitsNo PlaceboInvestigational MedicinesOncology

Blood Cancer Treatment: SMART101 After Stem Cell Transplant

We are studying the safety and effectiveness of SMART101 for patients with blood cancers after stem cell transplantation. The goal is to see if it helps improve immune recovery and reduce complications.

Allogenic Stem Cell Transplantation>2 yearsSafety phase (I)Efficacy phase (II)11-15 visitsNo PlaceboInvestigational MedicinesHematologyInfectious Diseases

C3-Glomerulopathy: Testing CPV-104

We are examining the safety and how the body processes CPV-104 in healthy individuals and patients with C3-Glomerulopathy. This study aims to gather important information about this new treatment.

C3 Glomerulopathy1-2 yearsSafety phase (I)Nephrology

Oxytocin and Trust Learning in Attachment Development

We are exploring how oxytocin may influence trust learning and cognitive flexibility in a virtual reality setting. This study aims to understand its effects on social bonding and learning processes.

Healthy Children>2 yearsSafety phase (I)Efficacy phase (II)≤5 visitsStandard MedicinesPsychiatry

Hepatocellular Cancer and Lung Cancer: ABBV-324 vs. Lenvatinib

We are comparing an intravenous treatment to an oral medication for adults with hepatocellular cancer or squamous-cell lung cancer. The study aims to assess side effects and changes in disease activity.

Liver CancerNon-Small Cell Lung Cancer>2 yearsSafety phase (I)Oncology

DMT: Study in Healthy Volunteers

We are investigating the effects of DMT in healthy individuals to understand its safety and potential benefits. This research may help us learn more about how DMT works in the body.

Stroke>2 yearsSafety phase (I)Neurology

Skin Irritation Study: New 5% Lidocaine Plaster

We are testing a new medicated plaster to see if it causes skin irritation or sensitization in healthy volunteers. This research aims to ensure the safety of the product for future use.

Post Herpetic Neuralgia6-12 monthsSafety phase (I)DermatologyNeurology

Small Cell Lung Cancer: 177Lu-EVG321 Treatment

We are testing a new drug to see if it is safe and how well the body tolerates it in patients with small cell lung cancer. This study aims to gather important information for future treatments.

Small Cell Lung Cancer>2 yearsSafety phase (I)OncologyPulmonology

Acute Myeloid Leukemia: Eganelisib Treatment Study

We are studying the safety and tolerability of eganelisib alone and with cytarabine in patients with relapsed or refractory acute myeloid leukemia. This trial aims to find the best dose and evaluate how well the treatment works.

Relapsed/Refractory Acute Myeloid LeukemiaHigher-Risk Myelodysplastic SyndromesSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesHematologyOncology

Advanced Solid Tumors: INP12 Treatment

We are evaluating the safety and how the body handles a new treatment called INP12 in patients with advanced solid tumors. This study aims to understand if INP12 is safe for further testing.

Solid Tumor>2 yearsSafety phase (I)Oncology

ABO-101 for Primary Hyperoxaluria Type 1

We are testing a new treatment, ABO-101, to see if it is safe and well-tolerated in people with Primary Hyperoxaluria Type 1. The study will also explore how the body reacts to the treatment.

Primary Hyperoxaluria>2 yearsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesPartially RemoteEndocrinologyNephrology

Cancer Anorexia: ART27.13 Cannabinoid Study

We are testing a new synthetic cannabinoid to see if it helps patients with cancer gain weight and improve appetite. The study also looks at the safety and quality of life for participants.

Cancer Anorexia3-6 monthsSafety phase (I)Efficacy phase (II)6-10 visitsInvestigational MedicinesCost ReimbursementInternal MedicineOncology

HER2-Positive Breast Cancer: New Treatment Without Chemotherapy

We are studying a combination of trastuzumab, pertuzumab, and tucatinib for patients with stage II-III HER2-positive breast cancer. The goal is to evaluate the safety and initial effectiveness of this chemotherapy-free approach.

HER2 Positive Breast Cancer1-2 yearsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesPartially RemoteOncology

Linaprazan Glurate: Interaction with Antibiotic

We are investigating how a new medication affects the way an approved antibiotic works in healthy individuals. This study may help us understand better drug interactions.

Helicobacter Pylori InfectionGastroesophageal Reflux Disease (GERD)3-6 monthsSafety phase (I)GastroenterologyInternal Medicine

Cefiderocol in Peritoneal Dialysis Patients

We are studying how cefiderocol is processed in the body of patients receiving peritoneal dialysis. This research aims to improve treatment options for infections in these patients.

Patients Undergoing Peritoneal Dialysis>2 yearsSafety phase (I)Infectious DiseasesNephrology

Antibiotics: Single Dose Study

We are examining how a single dose of certain antibiotics is absorbed in the body of healthy volunteers. This research may help improve treatment strategies for infections.

Healthy VolunteersSafety phase (I)Infectious Diseases