Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord, leading to muscle weakness, difficulty speaking, and challenges with movement.
Acetyl-L-Carnitine for ALS Treatment
We are studying whether acetyl-L-carnitine can help slow down the progression of ALS and improve quality of life. Participants will receive different doses to see which is most effective and safe.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you 18 years old or older?
- Do you have a diagnosis of ALS (Amyotrophic Lateral Sclerosis)?
- Are you currently taking riluzole (brand name Rilutek) 50 mg twice a day or have you taken it for at least 4 weeks before the study?
- Are you pregnant, breastfeeding, or able to become pregnant without using effective birth control?
- Do you have any severe health conditions that could affect your survival or ability to participate in the study in the next year?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Nicetile
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Centro Clinico Nemo
Centro Clinico NeMO Ancona
Ancona, Italy
Centro Clinico Nemo
ALS center
Bresso, Italy
AOU di Modena Nuovo Ospedale Civile S. Agostino Estense di Modena- Ospedale di Baggiovara
Clinica Neurologica
Formigine, Italy
Sponsor: Istituto Di Ricerche Farmacologiche Mario Negri
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.