Leukaemia
Leukaemia is a type of cancer that affects the blood and bone marrow, leading to the overproduction of abnormal white blood cells. This can interfere with the body's ability to fight infections and produce healthy blood cells.
Activated T-Cells for Graft vs Host Disease After Stem Cell Transplant
We are testing a new treatment using activated regulatory T-cells in patients shortly after stem cell transplantation. The aim is to see if it can safely reduce the risk and severity of acute graft vs host disease.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Acute graft versus host disease
Acute graft versus host disease occurs when donor immune cells attack the recipient's body after a stem cell or bone marrow transplant, leading to symptoms that can affect the skin, liver, and gastrointestinal tract.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you at least 18 years old?
- Do you have a blood cancer like leukemia, lymphoma, or multiple myeloma that needs a stem cell transplant?
- Are you currently pregnant or breastfeeding?
- Have you had any other cancer in the last 3 years?
- Are you taking high doses of steroids like Prednisone or Dexamethasone?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Allogeneic T Lymphocytes
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Kath. St. Paulus GmbH
Klinik für Innere Medizin II
Dortmund, Germany
Technische Universitaet Dresden
Early Clinical Trial Unit (NCT/UCC ECTU)
Dresden, Germany
Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR
III. Medizinische Klinik und Poliklinik – Haematologie und Medizinische Onkologie
Mainz, Germany
Sponsor: ActiTrexx GmbH
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.