Acute Myeloid Leukemia: CD19 CAR-T Cell Therapy

We are studying the safety of a new CAR-T cell treatment for patients with refractory acute myeloid leukemia. This trial aims to see how well the treatment works and how long the CAR-T cells last in the body.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cyclophosphamide Sandoz
Cyclophosphamide Sandoz is a chemotherapy medicine used to treat various cancers and some severe autoimmune conditions by suppressing the immune system.
Fludarabine Accord
Fludarabine Accord is a chemotherapy medicine used to treat certain types of blood cancers such as chronic lymphocytic leukemia.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cyclophosphamide
Cyclophosphamide is a cancer-fighting and immune-suppressing substance used to treat various cancers and some severe autoimmune conditions.
Fludarabine Phosphate
Fludarabine phosphate is used to treat certain blood cancers, especially chronic lymphocytic leukemia and some lymphomas.
Tisagenlecleucel
Tisagenlecleucel is a cell-based therapy that uses a patient's own modified immune cells to target and kill certain B-cell cancers.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Mb-Cart19.1

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Bendarabin
Beneflur
Ciclofosfamida Accord

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire De Lille
Unité de Thérapie Cellulaire – Service des Maladies du Sang
Loos, France
Sponsor: Centre Hospitalier Universitaire De Lille
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.