Acute Myeloid Leukemia: CHIP-AML22 Trial

We are studying new treatment options for children and adolescents with newly diagnosed AML to see if they improve survival and reduce side effects compared to standard therapies.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cardioxane
Cardioxane is a medicine used to protect the heart from damage caused by certain chemotherapy drugs.
Di-Adreson-F Aquosum
Etopophos
Etopophos is a chemotherapy medicine used to treat several types of cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cytarabine
Cytarabine is a chemotherapy substance used to treat certain blood cancers, especially acute leukemias.
Daunorubicin Hydrochloride
Daunorubicin hydrochloride is a cancer-fighting substance used to treat certain blood cancers like leukemia by killing rapidly dividing cancer cells.
Dexrazoxane
Dexrazoxane is a substance that helps protect the heart from damage caused by certain chemotherapy drugs.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Daunorubicin
Methotrexate

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abix
Acecort
Actocortina

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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UZ Leuven
Pediatric Hemato-Oncology
Heverlee, Belgium
Association Hospitaliere De Bruxelles Hopital Universitaire Des Enfants Reine Fabiola
Pediatric Hemato-Oncology
Jette, Belgium
Universitair Ziekenhuis Gent
Pediatric Hemato-Oncology
Ledeberg, Belgium

Sponsor: Prinses Maxima Centrum voor Kinderoncologie B.V.
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.