Acute Myeloid Leukemia: Comparing Treatment Regimens

We are studying two different conditioning regimens for adults with acute myeloid leukemia before stem cell transplantation. The goal is to see which regimen may improve survival and recovery outcomes.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cellcept
Cellcept is a medicine that helps prevent a transplanted organ from being rejected by the immune system.
Clofarabine Synthon
Clofarabine Synthon is a chemotherapy medicine used to treat certain blood cancers, including some types of leukemia.
Flucortac

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Anti-T Lymphocyte Immunoglobulin For Human Use
Anti-T lymphocyte immunoglobulin is a preparation of antibodies that reduces activity of immune T cells to prevent or treat organ transplant rejection.
Busulfan
Busulfan is a substance used to destroy bone marrow cells before a bone marrow transplant and to treat certain blood cancers.
Ciclosporin
Ciclosporin is a substance that suppresses the immune system to prevent organ transplant rejection and treat autoimmune conditions.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Astonin
Astonin H
Capimune

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire Amiens Picardie
service d'hématologie- soins intensifs, greffes
Amiens, France
Centre Hospitalier Regional Et Universitaire De Brest
service d'hématologie
Brest, France
Centre Hospitalier Universitaire De Caen Normandie
service d'hématologie clinique
Caen, France

Sponsor: Centre Hospitalier Universitaire De Nantes
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.