Acute Myeloid Leukemia: CPX-351 vs. Standard Chemotherapy

We are studying whether a new treatment called CPX-351 can help patients with specific types of acute myeloid leukemia achieve better remission compared to standard chemotherapy. This trial focuses on patients with de novo intermediate or adverse risk AML.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cytarabine
Idarubicin Accord
Idarubicin Accord is a chemotherapy medicine used to treat certain types of leukemia, including acute myeloid leukemia.
Vyxeos Liposomal
Vyxeos Liposomal is a chemotherapy medicine used to treat certain types of acute myeloid leukemia.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cytarabine
Cytarabine is a chemotherapy substance used to treat certain blood cancers, especially acute leukemias.
Daunorubicin
Daunorubicin is a substance used to treat certain types of cancer, especially leukemias, by killing rapidly dividing cancer cells.
Daunorubicin Hydrochloride
Daunorubicin hydrochloride is a cancer-fighting substance used to treat certain blood cancers like leukemia by killing rapidly dividing cancer cells.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alexan
Ara-Cell
Aracytin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire Amiens-Picardie
Hématologie
Amiens, France
Centre Hospitalier D Avignon
Hématologie
Avignon, France
CHUR Of Besançon
Hématologie
Besançon, France

Sponsor: Centre Hospitalier Universitaire De Nice
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.