Acute Myeloid Leukemia: Low Intensity Therapy Study

We are exploring whether a gentler treatment approach helps patients with relapse or refractory acute myeloid leukemia live longer and feel better compared to stronger therapies.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Azacitidine
Cytarabine
Etoposide
Etoposide is a chemotherapy medicine used to treat various types of cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Amsacrine
Amsacrine is a substance used to treat certain cancers, especially leukemia, by interfering with cancer cell DNA replication.
Azacitidine
Azacitidine is a substance that treats certain bone marrow disorders and blood cancers by slowing abnormal blood cell growth and restoring healthier blood production.
Cladribine
Cladribine is a substance that reduces specific immune cells to help control relapsing forms of multiple sclerosis.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alexan
Ara-Cell
Aracytin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Fakultni Nemocnice Brno
Internal Medicine, Hematology and Oncology
Brno, Czechia
Fakultni Nemocnice Ostrava
Haematooncology
Hlučín, Czechia
Fakultni Nemocnice Hradec Kralove
Hematology
Hradec Králové, Czechia

Sponsor: Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori IRST S.r.l.
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.