Acute Myeloid Leukemia: Midostaurin and Gemtuzumab Ozogamicin

We are studying a new combination treatment for patients with acute myeloid leukemia to see if it is safe and effective alongside standard chemotherapy.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cytarabine
Mylotarg
Mylotarg is a cancer medicine used to treat acute myeloid leukemia, a type of blood cancer.
Rydapt
Rydapt is a cancer medicine used to treat certain types of blood cancers, including some forms of acute myeloid leukemia and advanced systemic mastocytosis.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cytarabine
Cytarabine is a chemotherapy substance used to treat certain blood cancers, especially acute leukemias.
Daunorubicin Hydrochloride
Daunorubicin hydrochloride is a cancer-fighting substance used to treat certain blood cancers like leukemia by killing rapidly dividing cancer cells.
Gemtuzumab Ozogamicin
Gemtuzumab ozogamicin is a targeted cancer treatment used to destroy leukemia cells in people with certain forms of acute myeloid leukemia.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alexan
Ara-Cell
Aracytin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Klinikum Chemnitz gGmbH
Klinik für Innere Medizin III
Chemnitz, Germany
Technische Universitaet Dresden
Medizinische Klinik und Poliklinik I
Dresden, Germany
HELIOS Klinikum Duisburg GmbH
Helios St. Johannes Klinik Duisburg / Medizinische Klinik 2
Duisburg, Germany

Sponsor: Technische Universitaet Dresden
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.