Acute Myeloid Leukemia: RVU120 with Venetoclax

We are studying a new treatment combining RVU120 and Venetoclax for patients with acute myeloid leukemia who did not respond to earlier therapies. The goal is to assess its safety and effectiveness in improving their condition.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Fem7
Venclyxto
Venclyxto is a medicine used to treat certain types of blood cancer, including some forms of leukemia and lymphoma.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Estradiol
Estradiol is a hormone used to replace low estrogen and relieve menopausal symptoms.
Methyldibromo Glutaronitrile
Methyldibromo glutaronitrile is a preservative used to prevent bacteria and mold growth in cosmetics and personal care products.
Venetoclax
Venetoclax is a substance used to treat certain blood cancers by helping cancer cells die.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Sel120
Dihydro-9-methyl-2-(1-piperazinyl)-4h-imidazoquinoline

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Activelle
Activelle Low
Activelle Minor

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Le Mans
Centre de Cancérologie de la Sarthe
Coulaines, France
Centre Hospitalier Universitaire De Lille
Service des Maladies du sang
La Madeleine, France
Centre Hospitalier Universitaire Grenoble Alpes
Service d'Hématologie
La Tronche, France

Sponsor: Ryvu Therapeutics S.A.
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.