Acute Myeloid Leukemia: Sulfasalazine with Chemotherapy

We are studying the addition of sulfasalazine to standard chemotherapy for elderly patients with newly diagnosed acute myeloid leukemia. The goal is to evaluate safety and effectiveness compared to existing treatments.

>2 years 6-10 visits Safety phase (I)Efficacy phase (II)No Placebo Standard Medicines Oral InjectionHematologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cytarabine

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cytarabine

Cytarabine is a chemotherapy substance used to treat certain blood cancers, especially acute leukemias.

Idarubicin Hydrochloride

Idarubicin hydrochloride is a chemotherapy substance used to treat certain cancers, especially acute leukemias.

Sulfasalazine

Sulfasalazine is a substance that reduces inflammation in the intestines and joints, often used for ulcerative colitis and rheumatoid arthritis.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alexan

Ara-Cell

Aracytin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire De Caen Normandie

Hematology

Caen, France

Centre Hospitalier Universitaire Amiens Picardie

Hematology

Colomiers, France

Assistance Publique Hopitaux De Paris

Hematology

Créteil, France

Sponsor: Assistance Publique Hopitaux De Paris

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.