ADHD and Depression: Dexamfetamine Formulations Study

We are investigating the safety and effectiveness of two dexamfetamine sulfate formulations for adults with ADHD and moderate to severe depression. This study aims to see how these treatments compare to a placebo in improving symptoms and managing side effects.

3-6 months ≤5 visits Efficacy phase (II)Investigational Medicines OralPsychiatry

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Attentin

Attentin is a stimulant medicine used to help improve focus and reduce hyperactivity in people with attention-deficit/hyperactivity disorder.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Atomoxetine

Atomoxetine is a substance that helps improve attention and reduce impulsivity and hyperactivity in people with attention deficit hyperactivity disorder.

Dexamfetamine Sulfate

Dexamfetamine sulfate is a stimulant that increases attention and reduces impulsivity and excessive sleepiness in people with ADHD or narcolepsy.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Attentin

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Adhesa

Amfexa

Attadex

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Universitaetsklinikum Bonn AöR

Psychiatry and Psychotherapy

Bonn, Germany

Goethe University Frankfurt

Psychiatry, Psychosomatics and Psychotherapy

Frankfurt am Main, Germany

Universitaet Leipzig

Polyclinic for Psychiatry and Psychotherapy

Leipzig, Germany

Sponsor: Fraunhofer Institute For Translational Medicine And Pharmacology ITMP

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.