Breast Cancer
Breast cancer is a type of cancer that forms in the cells of the breasts, often presenting as a lump or mass. It can affect both men and women, though it is much more common in women.
Advanced Cancer: AZD8205 Treatment Study
We are studying the safety and early effectiveness of AZD8205, both alone and with other cancer treatments, for people with advanced or metastatic solid tumors. This research aims to find the best dose and understand how the drug works in the body.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Ovarian Cancer
Ovarian cancer begins in the ovaries and can cause symptoms like abdominal bloating, pelvic pain, and changes in bowel habits. It is often diagnosed at a later stage.
Endometrial Cancer
Endometrial cancer starts in the lining of the uterus and is often associated with abnormal vaginal bleeding. It is the most common type of uterine cancer.
Biliary Neoplasm
Biliary neoplasm refers to cancer that occurs in the bile ducts, which can lead to symptoms like jaundice, abdominal pain, and weight loss.
Non-Small Cell Lung Cancer
Non-small cell lung cancer is a type of lung cancer that is more common than small cell lung cancer. It can cause symptoms like a persistent cough, chest pain, and shortness of breath.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you at least 18 years old?
- Do you have metastatic or locally advanced breast cancer, ovarian cancer, or lung cancer?
- Are you currently taking any steroids or immunosuppressive medications?
- Have you had any major heart problems like a heart attack or severe heart failure in the last 6 months?
- Do you have an active infection, such as tuberculosis or HIV?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Rilvegostomig
Azd8205
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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UZ Leuven
Gynaecological oncology
Heverlee, Belgium
Institut Jules Bordet
Clinical Trials Conduct Unit
Negenmanneke, Belgium
Institut Regional Du Cancer De Montpellier
Oncologie médicale
Grabels, France
Sponsor: AstraZeneca AB
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.