Advanced Colorectal Cancer: FOLFIRI and Cetuximab Treatment

We are studying whether a combination of FOLFIRI and Cetuximab is effective for patients with advanced colorectal cancer who have specific genetic markers. This research aims to improve first-line treatment options for these patients.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Irinotecan
Irinotecan is a chemotherapy medicine used to treat certain cancers, especially colorectal cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cetuximab
Cetuximab is a substance that targets a protein on cancer cells to help slow or stop growth in colorectal and head and neck cancers.
Fluorouracil
Fluorouracil is a substance used to treat cancer by stopping the growth of cancer cells.
Folinic Acid
Folinic acid is a substance that helps restore folate levels and protects healthy cells during certain chemotherapy treatments.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Campto
Canri
Chlorhydrate D'irinotécan Trihydraté Sun

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Ospedale Civile San Giovanni di Dio - Frattamaggiore
U.O.C. Oncologia
Frattamaggiore, Italy
Presidio Ospedaliero Santa Maria delle Grazie
Oncologia Medica
Pozzuoli, Italy
IRCCS Istituto Nazionale Tumori Fondazione Pascale
SSD Terapie innovative nelle metastasi addominali
Soccavo, Italy
Sponsor: IRCCS Istituto Nazionale Tumori Fondazione Pascale
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.