Advanced Colorectal Cancer: OMTX705 Combination Therapy

We are studying a new drug, OMTX705, combined with regorafenib and tislelizumab for patients with advanced colorectal cancer. The goal is to evaluate its safety and effectiveness in those who have not responded to previous treatments.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Stivarga
Stivarga is a cancer medicine used to treat certain advanced colorectal, liver, and gastrointestinal tumors.
Tevimbra

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Regorafenib
Regorafenib is a substance that helps slow tumor growth by blocking signals cancer cells and the blood vessels feeding them need to grow.
Tislelizumab
Tislelizumab is a cancer immunotherapy substance that helps the immune system attack tumor cells by blocking a protein called PD-1 that restrains immune responses.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Omtx705

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Clinica Universidad De Navarra
Medical Oncology
Barañáin, Spain
Hospital Universitario Donostia
Medical Oncology
Donostia / San Sebastián, Spain
Institut Catala D'oncologia
Medical Oncology
L'Hospitalet de Llobregat, Spain

Sponsor: Oncomatryx Biopharma S.L.
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.