Advanced Dedifferentiated Liposarcoma: Pemigatinib and Retifanlimab Study

We are studying the effects of two medications on patients with advanced dedifferentiated liposarcoma. The goal is to see if they improve treatment outcomes and quality of life.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Pemazyre
Pemazyre is a cancer medicine used to treat certain bile duct cancers that have a specific genetic abnormality.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Pemigatinib
Pemigatinib is a substance that blocks proteins that help certain bile duct cancers grow when they have specific genetic changes.
Retifanlimab
Retifanlimab helps the immune system recognize and attack certain cancers by blocking a protein that suppresses immune responses.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Aarhus Universitetshospital
Department of Oncology
Århus, Denmark
Helse Bergen HF
Haukeland University Hospital, Department of Oncology Jonas Lies vei 65, 5021 Bergen, Norway
Bergen, Norway
Oslo University Hospital HF
Department of Oncology, Ullernchausseen 70, 0310 Oslo, Norway
Oslo, Norway

Sponsor: Region Skane
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.