Advanced Gastric Cancer: AZD0901 Treatment Study

We are studying how well AZD0901 works and its safety compared to standard treatments for adults with advanced gastric or gastroesophageal junction cancer that has high levels of a protein called CLDN18.2.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cyramza
Cyramza is a cancer medicine used to treat certain advanced or metastatic tumors, including stomach, lung, and liver cancers.
Docetaxel Hikma
Docetaxel Hikma is a chemotherapy medicine used to treat various types of cancer.
Irinotecan Accord
Irinotecan Accord is a chemotherapy medicine used to treat certain cancers, commonly colorectal cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Docetaxel
Docetaxel is a chemotherapy substance used to treat various cancers by stopping cancer cells from dividing.
Ethanol
Ethanol is a substance used as an antiseptic to kill germs and as a solvent in healthcare products.
Irinotecan
Irinotecan is a chemotherapy substance used to treat certain cancers by blocking cancer cells from dividing and growing.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Bendadocel
Paclitaxel
Azd0901

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Bendadocel
Camitotic
Campto

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Regional Et Universitaire De Brest
Medical Oncology
Guilers, France
Centre Hospitalier Universitaire De Lille
Oncology
Loos, France
Besancon University Hospital Center
Medical Oncology
Nantes, France

Sponsor: AstraZeneca AB
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.