Advanced Ovarian Cancer: Comparing Treatment Combinations

We are studying two different drug combinations to see which one helps patients with advanced ovarian cancer live longer without disease progression after surgery. This trial involves patients who have undergone complete initial surgery.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Mvasi
Mvasi is a cancer medicine used to treat several types of tumors by blocking the growth of blood vessels that feed the tumor.
Zejula
Zejula is a cancer medicine used to help prevent recurrence of ovarian, fallopian tube, or primary peritoneal cancer after chemotherapy.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Bevacizumab
Bevacizumab is a substance that blocks formation of new blood vessels to treat certain cancers and eye conditions caused by abnormal vessel growth.
Niraparib
Niraparib is a substance used to treat certain cancers by blocking cancer cells' ability to repair DNA, helping prevent tumors from returning.
Niraparib Tosilate Monohydrate
Niraparib tosilate monohydrate is a substance that helps treat certain cancers by blocking cancer cells' ability to repair damaged DNA.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abevmy
Alymsys
Avastin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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AZ Sint-Lucas & Volkskliniek
Oncology
Gent, Belgium
UZ Leuven
Gynaecological Oncology
Heverlee, Belgium
Centre Hospitalier Universitaire Dinant Godinne Sainte-Elisabeth-UCL-Namur
Oncology
Saint-Servais, Belgium

Sponsor: Arcagy Gineco
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.