Advanced Soft-Tissue Sarcomas: Next-Generation Sequencing Study

We are exploring whether high-throughput molecular analysis can help guide treatment for patients with advanced soft-tissue sarcomas. This study will compare treatment outcomes for those receiving NGS-guided therapy versus standard care.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Ibrance
Ibrance is a cancer medicine used with hormone therapy to treat certain types of advanced or spread breast cancer.
Imfinzi
Imfinzi is a cancer medicine that helps the immune system find and fight tumor cells.
Lynparza
Lynparza is a cancer medicine used to treat certain ovarian, breast, pancreatic, and prostate cancers, especially those caused by specific gene changes.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Capmatinib
Capmatinib is a substance that targets MET to treat certain non-small cell lung cancers with MET gene changes.
Ceritinib
Ceritinib is a substance that blocks an abnormal ALK protein to help control certain lung cancers.
Dabrafenib
Dabrafenib is a substance that targets a specific gene mutation to treat certain cancers, especially melanoma.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Daurismo
Mekinist

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Brastib
Finlee
Krufton

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Institut De Cancerologie De L Ouest
Medical Oncology
Avignon, France
Centre Jean Perrin
Medical Oncology
Beaumont, France
Institut Bergonie
Medical Oncology
Bordeaux, France

Sponsor: Institut National De La Sante Et De La Recherche Medicale
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.