Advanced Solid Tumors: [68Ga]Ga-DPI-4452 and [177Lu]Lu-DPI-4452 Study

We are studying the safety and effectiveness of two new treatments for patients with advanced solid tumors that cannot be removed by surgery. This trial also looks at how well these treatments can help in imaging the tumors.

6-12 months Safety phase (I)Efficacy phase (II)No Placebo Cost Reimbursement Investigational Medicines Oral InjectionOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Diamox

Diamox is a medicine used to prevent and treat altitude sickness and to lower eye pressure in glaucoma.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Acetazolamide

Acetazolamide is a substance that reduces fluid retention and lowers eye pressure, often used for glaucoma and to prevent altitude sickness.

Acetazolamide Sodium

Acetazolamide sodium is a substance that helps remove excess fluid and lowers eye pressure, commonly used for glaucoma and to prevent altitude sickness.

Gallium (68ga) Chloride

Gallium-68 chloride is a radioactive tracer used in PET scans to help visualize tumors, infections, and other abnormal tissues.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Dpi-4452

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acemit

Acetazolamid Agepha

Acetazolamida Arena

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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UZ Leuven

Nucleaire geneeskunde

Heverlee, Belgium

Institut Jules Bordet

Nucleaire geneeskunde

Negenmanneke, Belgium

Centre Jean Perrin

Oncology

Beaumont, France

Sponsor: ITM Oncologics GmbH

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.