Advanced Solid Tumors: AZD3470 Study

We are testing a new drug, AZD3470, for patients with advanced solid tumors lacking the MTAP gene. The study aims to evaluate its safety and effectiveness, both alone and with other cancer treatments.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Dextromethorphane Elerte
Dextromethorphane Elerte is a cough suppressant used to relieve dry, irritating coughs.
Midazolam Ratiopharm
Midazolam Ratiopharm is a medicine used to calm or sedate people before or during medical procedures.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dextromethorphan Hydrobromide
Dextromethorphan hydrobromide is a cough suppressant substance that helps reduce coughing from colds or throat irritation.
Midazolam
Midazolam is a substance that produces sedation and reduces anxiety, often used to calm patients before procedures or help control seizures.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Azd3470

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acatar Mono
Acodin
Acodin 150 Junior

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Institut Gustave Roussy
Département d'innovation thérapeutique et essais précoces (DITEP)
Villejuif, France
Institut Gustave Roussy
Département d'innovation thérapeutique et essais précoces (DITEP)
Villejuif, France
Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting
Clinical Pharmacology
Amstelveen, Netherlands

Sponsor: Astrazeneca AB
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.