Advanced Solid Tumors: AZD9574 Treatment Study

We are studying the safety and early effectiveness of AZD9574, both alone and with other cancer therapies, for patients with advanced solid tumors. This research aims to improve treatment options for those facing these challenging conditions.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Temozo-Cell
Temozolomid Ratiopharm
Temozolomid Ratiopharm is a cancer medicine used to treat certain brain tumors.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Datopotamab Deruxtecan
Datopotamab deruxtecan is an antibody-based substance that targets a protein called TROP2 to deliver chemotherapy directly to certain solid tumors.
Temozolomide
Temozolomide is a substance used in chemotherapy to treat certain types of brain tumors by slowing cancer cell growth.
Trastuzumab Deruxtecan
Trastuzumab deruxtecan is a targeted cancer treatment that attacks tumors with high HER2 protein levels.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Ds-8201a
Azd9574
Az14193391

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Advecit
Advecit
Blastomat

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Complexo Hospitalario Universitario A Coruna
7005: Oncologia Médica
A Coruña, Spain
Hospital Universitari Vall D Hebron
7002: Oncología Médica
Barcelona, Spain
University Hospital Virgen Del Rocio S.L.
7004: Oncología
Huelva, Spain

Sponsor: AstraZeneca AB
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.