Breast Cancer
Breast cancer is a type of cancer that forms in the cells of the breasts, often presenting as a lump or mass. It can affect both men and women, though it is much more common in women.
Advanced Solid Tumors: MK-8294 Treatment
We are evaluating a new treatment called MK-8294 for people with advanced solid tumors. The study aims to understand its safety and how well it works.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Cervical Squamous Cell Carcinoma
Cervical squamous cell carcinoma is a type of cancer that occurs in the cervix, often linked to human papillomavirus (HPV) infection. Early detection through screening can lead to better outcomes.
Endometrial Carcinoma
Endometrial carcinoma is cancer that begins in the lining of the uterus (endometrium). It is the most common type of uterine cancer and often presents with abnormal bleeding.
Esophageal Squamous Cell Carcinoma
Esophageal squamous cell carcinoma is a type of cancer that occurs in the esophagus, often associated with smoking and alcohol use. It can lead to difficulty swallowing and weight loss.
Head and Neck Squamous Cell Carcinoma
Head and neck squamous cell carcinoma refers to cancers that arise in the mucosal surfaces of the head and neck, often linked to tobacco and alcohol use. Symptoms can vary based on the location.
Bladder Cancer
Bladder cancer is a type of cancer that begins in the bladder's lining. It is more common in older adults and can cause symptoms like blood in urine and frequent urination.
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting
Clinical Research Unit
Amstelveen, Netherlands
Radboud universitair medisch centrum Stichting
Medical Oncology
Nijmegen, Netherlands
Sponsor: Merck Sharp & Dohme LLC
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.