Advanced Solid Tumors: ORIC-114 Study

We are testing a new drug, ORIC-114, for patients with advanced solid tumors that have EGFR or HER2 alterations. The study will assess its safety and effectiveness alone and with chemotherapy.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

L114

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Chelidonium Majus D2
Chelidonium majus D2 is a preparation from greater celandine traditionally used for liver and gallbladder-related digestive complaints.
Lycopodium Clavatum D3
Lycopodium Clavatum D3 is a homeopathic preparation traditionally used for digestive complaints like bloating, gas, and irregular bowel habits.
Mucuna Pruriens D6
Mucuna pruriens is a plant-derived substance commonly used to help relieve Parkinson's symptoms and to support male reproductive health.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Oric-114

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Uniwersyteckie Centrum Kliniczne
Ośrodek Badań Klinicznych Wczesnych Faz
Suchanino, Poland
Hospital Quironsalud Barcelona
Oncology
Barcelona, Spain
Hospital Universitari Vall D Hebron
Oncology
Barcelona, Spain

Sponsor: ORIC Pharmaceuticals Inc.
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.