Advanced Solid Tumors: S095035 Treatment Study

We are investigating the safety and effectiveness of S095035, alone and with TNG462, for adults with advanced solid tumors that have a specific genetic deletion. This study aims to find the best dose and assess how well the treatment works.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Quetiapine Quetiapine 25 Mg Film-Coated Tablet
Quetiapine 25 mg tablets are a medicine used to treat schizophrenia and bipolar disorder.
Sigazix 50 Mg Tablete

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Quetiapine Fumarate
Quetiapine fumarate is an antipsychotic substance used to treat schizophrenia and bipolar disorder by helping balance brain chemicals that affect mood and thinking.
Sitagliptin
Sitagliptin is a substance that helps lower blood sugar in people with type 2 diabetes.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Tng462
S095035

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Adiabin
Adimuplan
Altuxerin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Rigshospitalet
Department of Oncology
Copenhagen, Denmark
Odense University Hospital
Onkologisk afdeling R
Odense, Denmark
Institut Bergonie
Unité de Phase Précoce
Bordeaux, France

Sponsor: Institut De Recherches Internationales Servier IRIS
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.