aHUS: Switching to Iptacopan Treatment

We are studying whether switching from anti-C5 antibody therapy to iptacopan can help people with aHUS avoid complications. The trial will also assess the safety and effects on blood and kidney health.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Iptacopan
Iptacopan is a substance that blocks part of the immune complement system to prevent red blood cell destruction in certain rare blood disorders.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Hopital Tenon
#2004:Soins intensifs néphrologiques et Rein Aigu
Bagnolet, France
CHU De Rouen
#2007: Néphrologie
Bois-Guillaume, France
Centre Hospitalier Universitaire De Bordeaux
#2006: Néphrologie – Transplantation-Dialyse – Aphérèse
Bordeaux, France

Sponsor: Novartis Pharma AG
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.