Alpha-1 Antitrypsin Deficiency: Prolastin® Self-Infusion Therapy

We are studying the safety of a self-infusion therapy with Prolastin® for patients with severe alpha-1-antitrypsin deficiency. The trial also looks at quality of life and patient satisfaction with this treatment.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Prolastin
Prolastin is a medicine given to people with an inherited protein deficiency to help protect their lungs from damage.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Human Alpha1-Proteinase Inhibitor
Human Alpha1-Proteinase Inhibitor is a substance that helps protect the lungs from damage in people with alpha-1 antitrypsin deficiency.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alfalastin
Plitalfa
Prolasplan

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Evangelische Lungenklinik Berlin Krankenhausbetriebs gGmbH
Klinik für Pneumologie
Bernau bei Berlin, Germany
Universitaetsklinikum Essen AöR
Department of Pulmonary Medicine
Essen, Germany
Goethe University Frankfurt
Medizinische Klinik 1: Pneumologie und Allergologie
Frankfurt am Main, Germany

Sponsor: Grifols S.A.
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.