Alzheimer's Disease and Down Syndrome: ACI-24.060 Study

We are testing a new treatment, ACI-24.060, to see if it is safe and can help generate an immune response in people with early Alzheimer's and adults with Down syndrome. This study will also look at its effects on brain amyloid levels.

>2 years 11-15 visits Safety phase (I)Efficacy phase (II)Cost Reimbursement Partially Remote Investigational Medicines InjectionNeurologyPsychiatry

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Neuraceq

Neuraceq is a PET imaging agent used to help detect brain changes linked to Alzheimer’s disease.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Florbetaben (18f)

Florbetaben (18F) is a radioactive imaging tracer used in PET scans to show amyloid plaque buildup in the brain for Alzheimer's evaluation.

Flortaucipir (18f)

Flortaucipir (18F) is a radioactive imaging tracer used in PET scans to visualize tau protein build-up in the brain.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Aci-24.060

Pal1-15 Acetate

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hospital De La Santa Creu I Sant Pau

Neurology

Barbastro, Spain

Fundacio ACE Institut Catala De Neurociencies Aplicades

Neurology

Barcelona, Spain

Hospital Universitario De La Princesa

internal Medicine

Ciudad Lineal, Spain

Sponsor: AC Immune S.A.

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.