Alzheimer's Disease: KarXT + KarX-EC Treatment

We are studying a new combination treatment for agitation in people with Alzheimer's disease. The goal is to see if it can reduce agitation symptoms better than a placebo.

3-6 months 11-15 visits Confirmation phase (III)Post-Trial Drug Access Cost Reimbursement Partially Remote Investigational Medicines OralNeurologyPsychiatry

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Karbox

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Oxcarbazepine

Oxcarbazepine is a substance that helps control seizures and reduce abnormal electrical activity in the brain.

Trospium Chloride

Trospium chloride is a substance that relaxes the bladder to reduce urgent, frequent, or leaking urination from an overactive bladder.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

KarXT

Xanomeline

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Apydan

Apydan Extent

Epilfarmo

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Medical Center Medconsult Pleven OOD

Psychiatry

Pleven, Bulgaria

Outpatient Clinic for Indiv. Practice for Spec.Med. Care in Psychiatry-Dr.Madlena Dimitrova Borisova

Psychiatry

Razgrad, Bulgaria

Medical Center Saint Naum EOOD

Psychiatry

Sofia, Bulgaria

Sponsor: Bristol-Myers Squibb Services Unlimited Company

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.