Alzheimer's Disease: MK-2214 Study

We are testing a new medication, MK-2214, in people with early Alzheimer's disease to see if it may slow the progression of brain changes. The study will also evaluate the safety of this treatment compared to a placebo.

>2 years >20 visits Efficacy phase (II)Post-Trial Drug Access Cost Reimbursement Investigational Medicines InjectionNeurology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Fludeoxyglucose (18f)

Fludeoxyglucose (18F) is a substance used in PET scans to help find and monitor cancer and other health problems.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Flortaucipir (18f)

Flortaucipir (18F) is a radioactive imaging tracer used in PET scans to visualize tau protein build-up in the brain.

Fludeoxyglucose (18f)

Fludeoxyglucose (18F) is a radioactive tracer used in PET scans to highlight areas of high metabolic activity, often for detecting cancer.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Mk-2214

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

[18f] Fdg

[18f] Fdg Βιοκοσμοσ

[18f] Fludeoxyglucose Biont

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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UZ Leuven

Neurologie

Heverlee, Belgium

Algemeen Ziekenhuis Groeninge

Neurologie

Kortrijk, Belgium

Cliniques Universitaires Saint-Luc

Neurologie

Sint-Stevens-Woluwe, Belgium

Sponsor: Merck Sharp & Dohme LLC

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.