Alzheimer's Disease: Rotigotine and Rivastigmine Study

We are testing a combination of rotigotine and rivastigmine to see if it improves thinking skills and daily activities in people with mild to moderate Alzheimer's disease. This study compares the new treatment to rivastigmine with a placebo.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Neupro
Neupro is a skin patch medicine used to treat Parkinson's disease symptoms and restless legs syndrome.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Rotigotine
Rotigotine is a substance that helps ease symptoms of Parkinson's disease and restless legs by mimicking dopamine's effects in the brain.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Dariante
Rotigotin Gebro
Rotigotin Luye

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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NeuropsychiatrieHK s.r.o.
NeuropsychiatrieHK
Hradec Králové, Czechia
Psychiatrie-ambulance s.r.o.
Psychiatrie-ambulance
Pilsen, Czechia
Vestra Clinics s.r.o.
Vestra Clinics
Rychnov nad Kněžnou, Czechia

Sponsor: Fondazione Santa Lucia IRCCS
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.