Alzheimer's Disease: The ExPlas Study on Plasma Transfusions

We are investigating whether plasma from exercise-trained donors is safe and can improve cognitive function in people with early Alzheimer's disease. This study will help us understand its effects over several years.

>2 years11-15 visitsEfficacy phase (II)Investigational MedicinesInjectionInternal MedicineNeurology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Octaplasma
Octaplasma is pooled human plasma used to replace proteins that help blood clot in people with bleeding or liver-related clotting problems.
Saline
Saline is a sterile saltwater solution used to hydrate patients, replace lost fluids, and rinse wounds or medical equipment.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Human Plasma Protein
Human plasma protein replaces essential blood proteins to treat low protein levels, bleeding disorders, and immune deficiencies.
Sodium Chloride
Sodium chloride is a substance used to replace salts and fluids in the body and to clean or irrigate wounds and nasal passages.
Sodium Chloride Solution 0.9%
Sodium chloride 0.9% is a sterile salt solution used to replace fluids and electrolytes, hydrate patients, and clean wounds or body cavities.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Other Plasma Protein Fractions

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acuolens
Addex Natriumklorid
Albumina Humana Csl Behring

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Norwegian University Of Science And Technolology
Department of Circulation and Medical Imaging
Trondheim, Norway
Sponsor: Norwegian University Of Science And Technolology
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.