Mild to Moderate Alzheimer's Disease
Mild to moderate Alzheimer's Disease is a progressive brain disorder that affects memory, thinking, and behavior, leading to difficulties in daily activities and communication.
Alzheimer’s Disease: KarXT + KarX-EC Treatment
We are studying a new treatment for cognitive impairment in people with mild to moderate Alzheimer’s disease. The trial will check if it helps improve thinking skills and daily activities, while also ensuring safety.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 60 and 85 years old?
- Do you have a designated caregiver who can help you for at least 10 hours a week?
- Do you have any severe medical conditions that could affect your safety or ability to participate in the study?
- Do you have a history of major depression, bipolar disorder, or severe psychiatric symptoms?
- Have you had any significant findings on a brain MRI that could affect your safety?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
KarXT
Xanomeline
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Apydan
Apydan Extent
Epilfarmo
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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CRST Helsinki Oy
CRST Helsinki Oy
Helsinki, Finland
Suomen Terveystalo Oy
Terveystalo Helsinki
Helsinki, Finland
University Of Eastern Finland
Brain Reserach Unit, Faculty of Medicine
Kuopio, Finland
Sponsor: Bristol-Myers Squibb Services Unlimited Company
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.