ANCA-Associated Vasculitis: Pioglitazone Treatment

We are studying whether adding pioglitazone to standard treatments can improve kidney function in patients with ANCA-associated vasculitis. The trial also looks at quality of life and potential side effects.

>2 years 11-15 visits Confirmation phase (III)Partially Remote Standard Medicines Oral InjectionNephrologyRheumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Actos

Actos is a medicine that helps lower blood sugar in adults with type 2 diabetes.

Paracetamol

Paracetamol relieves pain and reduces fever for conditions like headaches, muscle aches, and colds.

Prednisone Eg

Prednisone Eg is a steroid medicine that reduces inflammation and treats allergic, autoimmune, and other inflammatory conditions.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dexchlorpheniramine

Dexchlorpheniramine is a substance that relieves allergy symptoms like runny nose, sneezing, and itching.

Methylprednisolone

Methylprednisolone is a corticosteroid that reduces inflammation and calms an overactive immune system.

Methylprednisolone Sodium Hemisuccinate

Methylprednisolone sodium hemisuccinate is a corticosteroid substance that rapidly reduces inflammation and suppresses excessive immune and allergic responses.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

4-In-One Flu Relief

6 Years Plus Paracetamol Boots

Abacat

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...

Centre Hospitalier Universitaire D'Angers

Néphrologie, dialyse et Transplantation

Angers, France

Centre Hospitalier De Valenciennes

Médecine interne et Néphrologie

Anzin, France

Assistance Publique Hopitaux De Paris

Néphrologie

Bagnolet, France

Sponsor: Assistance Publique Hopitaux De Paris

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.