Anesthesia Study: Ketamine vs. Propofol Combinations

We are comparing the effectiveness of ketamine alone and a ketamine-propofol mix against standard propofol for safe tracheal intubation in patients at risk of aspiration during surgery. The goal is to see which option leads to fewer complications and better tolerance.

≤3 months Confirmation phase (III)No Placebo Standard Medicines InjectionInternal MedicineOtolaryngologyPsychiatry

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Ketamine

Ketamine is a medicine used to induce anesthesia for procedures and, in some cases, to help relieve severe depression.

Propofol

Propofol is a fast-acting anesthetic medicine used to put people to sleep for surgeries and other medical procedures.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Ketamine

Ketamine is a fast-acting anesthetic substance used to induce anesthesia, relieve severe pain, and sometimes help with treatment-resistant depression.

Propofol

Propofol is a substance that causes quick loss of consciousness and provides short-term sedation for surgeries and medical procedures.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Anesia

Anesia Baxter

Calypsol

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Regional D'Angers

Anaestesia

Angers, France

Hopital Tenon

Anaestesia

Bagnolet, France

Centre Hospitalier Universitaire De Toulouse

Anaestesia

Blagnac, France

Sponsor: Centre Hospitalier Universitaire De Nantes

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.