Antibiotic Treatment for Critically Ill Patients

We are studying whether a short course of high-dose antibiotics is as effective as standard treatment for critically ill patients with pneumonia, intra-abdominal infections, or bloodstream infections. This research may help reduce antibiotic use while maintaining patient safety.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cefotax
Cefotax is an antibiotic medicine used to treat serious bacterial infections such as pneumonia, bloodstream infections, and meningitis.
Ceftriaxone
Ceftriaxone is an antibiotic used to treat serious bacterial infections such as pneumonia, meningitis, and severe bloodstream infections.
Cefuroxime
Cefuroxime is an antibiotic medicine used to treat common bacterial infections of the lungs, sinuses, skin, and urinary tract.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cefotaxime
Cefotaxime is an antibiotic substance used to treat serious bacterial infections by stopping bacteria from growing.
Ceftriaxone
Ceftriaxone is an antibiotic substance used to treat serious bacterial infections and is usually given by injection.
Ceftriaxone Sodium
Ceftriaxone sodium is an antibiotic substance used to treat many serious bacterial infections, including pneumonia, bloodstream infections, and meningitis.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Agenor
Agenorem
Anaptivan

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Ziekenhuis Aan De Stroom
Intensive care unit
Antwerpen, Belgium
UZ Leuven
Intensive care unit
Heverlee, Belgium
Universitair Ziekenhuis Gent
Intensive care unit
Ledeberg, Belgium

Sponsor: Universitair Ziekenhuis Gent
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.