Anticoagulant Treatments for Intra-Cardiac Thrombus: The ARGONAUT Trial

We are comparing a new direct oral anticoagulant with a standard vitamin K antagonist in patients with intra-cardiac thrombus. The goal is to see which treatment better reduces complications and promotes thrombus regression.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Acenocoumarol Cf
Acenocoumarol Cf is a medicine that helps prevent harmful blood clots by thinning the blood.
Apixaban
Apixaban is a medicine that helps prevent dangerous blood clots and reduces the risk of stroke in people with an irregular heart rhythm.
Dabigatran Etexilate
Dabigatran etexilate is a medicine used to prevent and treat blood clots and lower the risk of stroke.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Acenocoumarol
Acenocoumarol is a substance that helps prevent harmful blood clots by thinning the blood.
Apixaban
Apixaban is a substance that helps prevent harmful blood clots and lowers stroke risk in people with irregular heart rhythm.
Dabigatran Etexilate
Dabigatran etexilate is a blood thinner that prevents and treats harmful blood clots and lowers stroke risk in people with irregular heartbeat.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abagat
Abatixent
Abidalo

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire De Nimes
CARDIOLOGIE
Milhaud, France
Sponsor: Centre Hospitalier Universitaire De Nimes
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.