Antiplatelet Therapy Reduction in High Bleeding Risk Patients

We are studying whether lowering the dose of antiplatelet medication helps patients with acute coronary syndrome who have had stents placed, while reducing the risk of bleeding. The trial compares different medication regimens to find the best balance between safety and effectiveness.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Clopidogrel Doc Generici
Clopidogrel Doc Generici is a medicine that helps prevent harmful blood clots to lower the risk of heart attacks and strokes.
Prasugrel
Prasugrel is a medicine used to help prevent dangerous blood clots in people with certain heart problems, especially after heart procedures.
Ticagrelor
Ticagrelor is a medicine that helps prevent dangerous blood clots in people after a recent heart attack, chest pain, or certain heart procedures.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Acetylsalicylic Acid
Acetylsalicylic acid is a substance that reduces pain, fever, and inflammation and can help prevent blood clots.
Clopidogrel
Clopidogrel is a substance that helps prevent blood clots by stopping platelets from sticking together, lowering the risk of heart attack and stroke.
Prasugrel
Prasugrel is a substance that prevents blood platelets from clumping, reducing the risk of clots after certain heart procedures.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Prasugrel

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aclop
Adagrel
Agrelan

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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ASST Grande Ospedale Metropolitano Niguarda
Cardiologia I Emodinamica
Bresso, Italy
Azienda Ospedaliero Universitaria Policlinico G Rodolico San Marco Di Catania
Unità di Cardiologia
Canalicchio, Italy
IRCCS Ospedale Policlinico San Martino
UOSD Cardiologia Interventistica
Genoa, Italy

Sponsor: Azienda Ospedaliera Universitaria Gaetano Martino Messina
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.