Artificial Cornea for Severe Corneal Ulcers

We are studying a new human-made cornea for patients with advanced corneal ulcers that don't improve with standard treatments. The trial aims to assess its safety and effectiveness in these challenging cases.

>2 yearsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesOphthalmology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Humanalbin
Humanalbin is a human blood protein solution used to restore blood volume and treat low blood protein levels.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Ex Vivo Expanded Autologous Human Corneal Epithelial Cells Containing Stem Cells
Patient's own corneal cells grown outside the body that contain stem cells are used to restore and repair a damaged corneal surface, improving vision.
Human Normal Immunoglobulin
Human normal immunoglobulin is a preparation of antibodies from healthy donors used to boost immune protection and treat certain immune-related disorders.
Human Plasma Protein
Human plasma protein replaces essential blood proteins to treat low protein levels, bleeding disorders, and immune deficiencies.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Alogenic Sclerocorneal Limbus Stem Adult Limbal Cells
Amniotic Membrane
Allogenic Corneal-Derived Adult Keratocytes

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Albumina Humana Csl Behring
Albumine Humaine Csl Behring
Biseko

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hospital Universitario Clinico San Cecilio
Servicio de Oftalmología
Armilla, Spain
Hospital San Juan de Dios del Aljarafe
Servicio de Oftalmología
Bormujos, Spain
Hospital Universitario Puerta Del Mar
Servicio de Oftalmología
Cadiz, Spain
Sponsor: Red Andaluza De Diseno Y Traslacion De Terapias Avanzadas Fundacion Publica Andaluza Progreso Y Salud
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.