Atherosclerotic Cardiovascular Disease
Atherosclerotic Cardiovascular Disease is a condition where plaque builds up in the arteries, leading to reduced blood flow and increasing the risk of heart attacks and strokes.
Atherosclerotic Cardiovascular Disease: Obicetrapib and Ezetimibe Study
We are testing a new combination therapy for people with atherosclerotic cardiovascular disease to see how it affects coronary plaque and overall heart health. This study aims to understand its safety and effectiveness compared to a placebo.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 45 and 80 years old?
- Do you have a history of heart disease, such as a heart attack or stroke?
- Are you currently taking cholesterol-lowering medications like Lipitor (atorvastatin) or Crestor (rosuvastatin)?
- Have you had any major heart events like a heart attack or stroke in the last 3 months?
- Do you have high blood pressure, with systolic pressure of 160 or higher or diastolic pressure of 100 or higher?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Obicetrapib
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Absorcol
Amisitela
Atorvastatín/Ezetimib Teva
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Fakultni Nemocnice U Sv Anny V Brne
I. Interni kardioangiologicka klinika
Brno, Czechia
Fakultni Nemocnice Hradec Kralove
III. Interni gerontometabolicka klinika
Hradec Králové, Czechia
Fakultni Nemocnice Plzen
II. Interni klinika
Pilsen, Czechia
Sponsor: NewAmsterdam Pharma B.V.
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.