Atrial Fibrillation
Atrial fibrillation (AF) is a heart condition characterized by an irregular and often rapid heartbeat, which can lead to poor blood flow and increase the risk of stroke and heart-related complications.
Atrial Fibrillation: Abelacimab Treatment Study
We are studying whether abelacimab can help high-risk patients with atrial fibrillation who cannot take oral blood thinners. The goal is to see if it reduces the risk of strokes and other serious complications compared to a placebo.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 65 and 74 years old and have a CHA2DS2VASc score of 4 or higher, or are you 75 years or older with a CHA2DS2VASc score of 3 or higher?
- Do you have atrial fibrillation (AF) or atrial flutter, as shown on an ECG or monitor?
- Have you had any major bleeding issues, like from the brain or stomach, in the past?
- Are you currently taking any blood thinners like Warfarin, Apixaban, or Rivaroxaban?
- Are you pregnant or able to become pregnant?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Abelacimab
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Mnogoprofilna Bolnitsa Za Aktivno Lechenie Puls AD
Cardiology department
Blagoevgrad, Bulgaria
Universitetska Mnogoprofilna bolnica za aktivno lechenie Deva Maria EOOD
Clinic of Сardiology
Dulovo, Bulgaria
Multiprofile Hospital For Active Treatment-Uni Hospital Ltd.
Clinic of cardiology
Elin Pelin, Bulgaria
Multiprofile Hospital For Active Treatment Dr. Tota Venkova AD
Cardiology department
Gabrovo, Bulgaria
Diagnostics And Consultancy Center Sveti Georgi EOOD
Haskovo, Bulgaria
Multidisciplinary Hospital For Active Treatment Haskovo AD
Cardiology department
Haskovo, Bulgaria
Umbal - Prof. D-R Stoyan Kirkovich AD
Clinic of cardiology
Kardzhali, Bulgaria
Multiprofile Hospital For Active Treatment Pazardzik AD
Cardiology department
Pazardzhik, Bulgaria
University Multiprofile Hospital For Active Treatment And Emergency Medicine N I Pirogov
Clinic of Сardiology
Pernik, Bulgaria
Medical Center Medconsult Pleven OOD
Pleven, Bulgaria
Multi-profile Hospital for Active Treatment Heart and Brain EAD
Clinic of Cardiology
Pleven, Bulgaria
Mbal Sveta Karidad EAD
Cardiology department
Plovdiv, Bulgaria
Multiprofile Hospital For Active Treatment Medical Complex Sveti Ivan Rilski EOOD
Plovdiv, Bulgaria
University Multiprofile Hospital For Active Treatment Saint Georgi EAD
Clinic of cardiology
Plovdiv, Bulgaria
University Multiprofile Hospital For Active Treatment Saint Georgi EAD
Clinic of cardiology
Plovdiv, Bulgaria
University Multiprophy Hospital For Active Treatment - Plovdiv AD
Second department of cardiology
Plovdiv, Bulgaria
Specialized Hospital For Active Cardiology Treatment Medica Kor EAD
Cardiology department
Ruse, Bulgaria
Group Practice For Specialized Medical Care Inakor Ltd.
Sliven, Bulgaria
MBAL Dr. Ivan Seliminski - Sliven AD
Cardiology department
Sliven, Bulgaria
Multiprofile Hospital For Active Treatment Dr. Bratan Shukerov AD
Cardiology department
Smolyan, Bulgaria
Alexandrovska University Hospital
Clinic of Сardiology
Sofia, Bulgaria
Medical center NeoGeneX Ltd.
Sofia, Bulgaria
Medical Center Sun I Zdrave Ltd.
Sofia, Bulgaria
Medical centre Kardiohelp EOOD
Sofia, Bulgaria
Military Medical Academy
Clinic of Сardiology
Sofia, Bulgaria
Multiprofile Hospital For Active Treatment Knyaginya Klementina Sofia EAD
Cardiology department
Sofia, Bulgaria
Tokuda Hospital
Clinic of Сardiology
Sofia, Bulgaria
Uniteversity Muliprofile Hospital For Active Treatment Tsaritsa Yoanna-Isul EAD
Clinic of Сardiology
Sofia, Bulgaria
University Hospital St. Anna
Clinic of Internal diseases
Sofia, Bulgaria
University Multidisciplinary Hospital For Active Treatment Sveta Ekaterina EAD
Clinic of cardiology
Sofia, Bulgaria
Diagnostic Consultative Centre Ascendent OOD
Tutrakan, Bulgaria
General Hospital Zabok And Hospital Of Croatian Veterans
Cardiology
Krapina, Croatia
Specijalna Bolnica Za Medicinsku Rehabilitaciju Krapinske Toplice
Cardiology
Krapina, Croatia
Klinicki Bolnicki Centar Osijek
Institute for heart and vascular diseases
Osijek, Croatia
Clinical Hospital Centre Rijeka
Clinic for heart and blood vessel diseases
Rijeka, Croatia
Opca Bolnica Zadar
Cardiology
Zadar, Croatia
BONIFARM d.o.o. za zastupanje i usluge
Cardiology
Zagreb, Croatia
Klinicki bolnicki centar Sestre milosrdnice
Clinic for heart and blood vessel diseases
Zagreb, Croatia
University Hospital Centre Zagreb
Clinic for heart and blood vessel diseases
Zagreb, Croatia
University Hospital Sveti Duh
IInstitute of cardiovascular diseases
Zagreb, Croatia
Medicus Services s.r.o.
Kardiologická ambulance
Brandýs nad Labem-Stará Boleslav, Czechia
Kardiologie-Liberec s.r.o.
Cardiology
Liberec, Czechia
Cerebrovaskularni poradna s.r.o.
Neurologicki ambulance
Ostrava, Czechia
Polabska zdravotni s.r.o.
Kardiologická ambulance
Poděbrady, Czechia
Fakultni Nemocnice Kralovske Vinohrady
Arytmologie
Prague, Czechia
Vseobecna Fakultni Nemocnice V Praze
interní klinika – koronární jednotka
Prague, Czechia
Vseobecna Fakultni Nemocnice V Praze
interní klinika
Prague, Czechia
Fakultni Nemocnice V Motole
Cardiology
Stodůlky, Czechia
Kardiologicka ambulance MUDr. Ferkl s.r.o.
Kardiologická ambulance
Trutnov, Czechia
Krajska zdravotni a.s.
Department of internal medicine
Ústí nad Labem, Czechia
East Tallinn Central Hospital
Department of neurology
Tallinn, Estonia
Laane-Tallinna Keskhaigla AS
Department of neurology
Tallinn, Estonia
North Estonia Medical Centre Foundation
Department of cardiology
Tallinn, Estonia
HUS-Yhtymae
Helsinki, Finland
North Karelia Central Hospital
Joensuu, Finland
Turku University Hospital
Turku, Finland
Klinikum Altenburger Land GmbH
Altenburg, Germany
Klinische Forschung Berlin-Mitte GmbH
Berlin, Germany
Klinische Forschung Dresden GmbH
Dresden, Germany
Klinische Forschung Hamburg GmbH
Hamburg, Germany
University Medical Center Hamburg-Eppendorf
Hamburg, Germany
Klinische Forschung Hannover-Mitte GmbH
Hannover, Germany
Klinikum der Stadt Ludwigshafen am Rhein gGmbH
Ludwigshafen am Rhein, Germany
Private practice of Dr TAGGESELLE
Markkleeberg, Germany
St. Vincenz Krankenhaus GmbH
Paderborn, Germany
Klinische Forschung Schwerin GmbH
Schwerin, Germany
Mediterraneo Hospital
Cardiology Department- Interventional Cardiology
Agía Paraskeví, Greece
Alexandra Hospital
Department of Clinical Therapeutics
Athens, Greece
Evgenidion Clinic Agia Trias S.A.
Cardiology Department
Athens, Greece
General Hospital Of Ioannina G. Hatzikosta
Cardiology department
Ioánnina, Greece
General University Hospital Of Larissa
University Cardiology Department
Lárisa, Greece
General Hospital of Elefsina “Thriassio”
Department of Cardiology
Mándra, Greece
General Hospital Of Nea Ionia Konstantopouleio Patision
Cardiology department
Néa Ionía, Greece
General University Hospital Of Patras
Department of Cardiology
Pátra, Greece
University General Hospital Of Thessaloniki Ahepa
A' Propaedeutic Department
Sykiés, Greece
University General Hospital Of Thessaloniki Ahepa
1st Cardiology Department
Sykiés, Greece
Diagnostic & Therapeutic Center Of Athens Hygeia Single Member S.A.
7th Cardiology Clinic
Távros, Greece
Asklepieion Voulas General Hospital
Cardiology department
Voúla, Greece
Athens Naval Hospital
1st Cardiology Department
Výronas, Greece
Henry Dunant Hospital Center
1st Cardiology Department
Zográfos, Greece
Metropolitan General Hospital
1rst Cardiology department
Zográfos, Greece
Pericardio Kft.
Békéscsaba, Hungary
Budapesti Szent Ferenc Korhaz
Cardiology rehabilitation
Budakeszi, Hungary
Central Hospital Of Northern Pest Military Hospital
Cardiology
Budapest, Hungary
Obudai Egeszsegugyi Centrum Kft.
Budapest, Hungary
Obudai Egeszsegugyi Centrum Kft.
Budapest, Hungary
Privat Doktor Egeszseguegyi Szolgaltato Zrt.
Cardiology
Budapest, Hungary
Semmelweis University
Budapest, Hungary
Semmelweis University
Budapest, Hungary
Budapesti Jahn Ferenc Del Pesti Korhaz Es Rendelointezet
Cardiology
Dunaharaszti, Hungary
Bugat Pal Korhaz Kht.
Gyöngyös, Hungary
Somogy Megyei Kaposi Mor Oktato Korhaz
Kaposvár, Hungary
Pest Megyei Flor Ferenc Korhaz
Kistarcsa, Hungary
Medifarma-98 Kft.
Nyíregyháza, Hungary
Coromed-Smo Kft.
Pécs, Hungary
University Of Pecs
Pécs, Hungary
University Of Szeged
Internal Medicine
Szeged, Hungary
Veszprémi Szív és Egészség Centrum (Dr. Sydó és Társa Kft.)
Veszprém, Hungary
Obudai Egeszsegugyi Centrum Kft.
Zalaegerszeg, Hungary
I.N.R.C.A. Istituto Nazionale Di Riposo E Cura Per Gli Anziani
Dpt. “Percorsi Medici”
Ancona, Italy
Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico
Department of Medical and Surgical Sciences
Bologna, Italy
Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia
Cardiothoracic Department
Brescia, Italy
ASST Grande Ospedale Metropolitano Niguarda
Cardiology
Bresso, Italy
Azienda Socio Sanitaria Locale N. 8 Di Cagliari
Cardiology and intensive coronary care unit
Cagliari, Italy
Azienda Ospedaliera Sant Anna E San Sebastiano Di Caserta
Cardiovascular Department
Caserta, Italy
Azienda Unita Sanitaria Locale Della Romagna
Internal Medicine
Faenza, Italy
Azienda Ospedaliero Universitaria Careggi
DAI Cardiotoracovascolare/Malattie aterotrombotiche
Florence, Italy
Irccs San Raffaele Roma S.r.l.
Cardio-Polomare
La Massimina-Casal Lumbroso, Italy
Azienda Ospedaliera Pugliese Ciaccio
Hemato-Oncology
Lamezia Terme, Italy
Alessandro Manzoni Hospital
Cardiology
Lecco, Italy
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone
Internal Medicine
Palermo, Italy
Azienda Ospedaliero Universitaria Parma
Cardio-toraco-vascolare
Parma, Italy
Azienda Ospedaliero Universitaria Pisana
U.O Medicina D'Urgenza Universitaria
Pisa, Italy
Fondazione Toscana Gabriele Monasterio
Electrophysiology
Pisa, Italy
Azienda Ospedaliera Universitaria Federico II Di Napoli
Dept of Advanced Biomedical Sciences
Piscinola, Italy
Ospedale Giovanni Paolo II
Cardiology
Ragusa, Italy
Azienda Unita Sanitaria Locale Della Romagna
Cardiology
Rimini, Italy
Azienda Sanitaria Locale TO3
Cardiology
Rivoli, Italy
Azienda Ospealiero Universitaria Policlinico Umberto I
Internal Medicine and Medical Specialties
Rome, Italy
Azienda Ospedaliero-Universitaria Sant Andre
Cardiology
Rome, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Dipartimento di Scienze di Laboratorio ed Ematologiche
Rome, Italy
San Camillo Forlanini Hospital
Stroke Unit
Rome, Italy
Centro Cardiologico Monzino S.p.A.
Heart Failure Unit
San Donato Milanese, Italy
Azienda Socio-Sanitaria Territoriale della Valle Olona
U.O Cardiologia
Saronno, Italy
Azienda Socio Sanitaria Territoriale Nord Milano
Medical Department
Sesto San Giovanni, Italy
Multimedica S.p.A.
Cardiology
Sesto San Giovanni, Italy
IRCCS Istituto Nazionale Tumori Fondazione Pascale
Cardiology
Soccavo, Italy
Azienda Ospedaliera Papa Giovanni XXIII
UOC SIMT - Centro Emostasi e Trombosi
Treviolo, Italy
Azienda Ospedaliera Ordine Mauriziano Di Torino
Cardiology
Turin, Italy
Azienda Socio Sanitaria Territoriale Dei Sette Laghi
Department of Emergency and Thrombosis and Hemostasis clinic
Varese, Italy
Balvu un Gulbenes slimnicu apvieniba SIA
Balvi, Latvia
Gk Neiroklinika
Berģi, Latvia
Rigas Austrumu kliniska universitates slimnica SIA
Cardiology department
Berģi, Latvia
Daugavpils Regional Hospital SIA
Cardiology department
Daugavpils, Latvia
Limbazu Slimnica SIA
Limbaži, Latvia
Pauls Stradins Clinical University Hospital
Cardiology department
Mārupe, Latvia
Rigas 1. slimnica SIA
Riga, Latvia
A. Ancanes gimenes arsta prakse
Salaspils, Latvia
Siguldas Slimnica
Sigulda, Latvia
Vidzemes Slimnica SIA
Department of Internal Disease
Valmiera, Latvia
Vidzemes Slimnica SIA
Valmiera, Latvia
Uniwersytecki Szpital Kliniczny W Bialymstoku
Klinika Kardiologii, Lipidologii i Chorób Wewnętrznych
Białystok, Poland
Kardiomed Janczewska Ostrowski Podjacka Reszka Skowronski Wojcik Lekarze Sp. p.
Elbląg, Poland
Synexus Polska Sp. z o.o.
Gdynia, Poland
Uniwersyteckie Centrum Medycyny Morskiej i Tropikalnej
Klinika Kardiologii i Chorób Wewnętrznych
Gdynia, Poland
Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki W Krakowie
Oddział Kliniczny Kardiologii oraz lnterwencji Sercowo-Naczyniowych
Grzegórzki, Poland
Kardio Brynow Sp z o.o.
Katowice, Poland
Revital Gabinet Kardiologiczny s.c. NZOZ Revital Kardiologia
Katowice, Poland
Krakowskie Centrum Medyczne Sp. z o.o.
Kraków, Poland
NZOZ ALL-MED Centrum Medyczne
Ksawerów, Poland
Beata Miklaszewicz & Dariusz Dabrowski Cardiamed Sp. j.
Legnica, Poland
NZOZ SALUSMED
Łódź, Poland
Samodzielny Publiczny Zaklad Opieki Zdrowotnej Centralny Szpital Kliniczny Uniwersytetu Medycznego W Lodzi
Klinika Elektrokardiologii
Łódź, Poland
1 Wojskowy Szpital Kliniczny Z Poliklinika samodzielny publiczny zakład opieki zdrowotnej W Lublinie
Oddział Kardiologii z Pracownią Hemodynamiki
Lublin, Poland
Samodzielny Publiczny Szpital Kliniczny Nr 4 W Lublinie
Klinika Kardiologii
Lublin, Poland
American Heart Of Poland S.A.
Oddział Kardiologii Inwazyjnej i Angiologii
Mielec, Poland
Uniwersyteckie Centrum Kliniczne Im. Prof. K. Gibinskiego Slaskiego Uniwersytetu Medycznego W Katowicach
Department of Internal Medicine and Clinical Pharmacology
Mikołów, Poland
Clinical Best Solutions Sp. z o.o. S.K.
Mokotów, Poland
Niepubliczny Zakład Opieki Zdrowotnej “Kardiologia Nowa Sól”
Nowa Sól, Poland
Medical University Of Warsaw
Klinika Kardiologii
Ochota, Poland
Narodowy Instytut Geriatrii Reumatologii I Rehabilitacji Im. Prof. Dr Hab. Med. Eleonory Reicher
Centrum Wsparcia Badań Klinicznych
Ochota, Poland
Futuremeds Sp. z o.o.
Olsztyn, Poland
Medicome Sp. z o.o.
Oświęcim, Poland
Uniwersytecki Szpital Kliniczny W Poznaniu
Poradnia Kardiologiczna
Poznań, Poland
Wojewodzki Szpital Im. Sw.Ojca Pio W Przemyslu
Cardiology Department
Przemyśl, Poland
Centrum Medyczne Medyk Sp. z o.o.
Rzeszów, Poland
Futuremeds Sp. z o.o.
Targówek, Poland
American Heart Of Poland S.A.
X Oddział Kardiologii lnwazyjnej Elektrofizjologii oraz Elektroterapii
Tychy, Poland
Centrum Badan Klinicznych Piotr Napora Lekarze sp.p.
Wrocław, Poland
Futuremeds Sp. z o.o.
Wrocław, Poland
Slaskie Centrum Chorob Serca W Zabrzu
II Oddział Kardiologii i Angiologii
Zabrze, Poland
Futuremeds Sp. z o.o.
Zgierz, Poland
Futuremeds Sp. z o.o.
Żoliborz, Poland
Icz Healthcare Sp. z o.o.
Oddział Kardiologiczny
Żywiec, Poland
Clinica New Aid S.R.L.
Cardiology
Baciu, Romania
Spitalul Judetean De Urgenta Braila
Cardiology
Brăila, Romania
Thera Card S.R.L.
Cardiology
Braşov, Romania
Ecocard S.R.L.
Cardiology
Bucharest, Romania
Lotus Med S.R.L.
Cardiology
Bucharest, Romania
Spitalul Clinic De Urgenta Bucuresti
Cardiology
Bucharest, Romania
Spitalul Universitar De Urgenta Bucuresti
Cardiology
Bucharest, Romania
Spitalul Clinic Municipal Cluj-Napoca
Cardiology
Cluj-Napoca, Romania
Cardio Med S.R.L.
Cardiology
Craiova, Romania
Spitalul Clinic Judetean De Urgenta Craiova
Cardiology
Craiova, Romania
Spitalul Clinic Judetean De Urgenta Bihor
Cardiology
Oradea, Romania
Spitalul Clinic de Urgenta "Bagdasar-Arseni" Bucuresti
Cardiology
Popeşti-Leordeni, Romania
Spitalul Clinic De Urgenta Prof Dr Agrippa Ionescu
Cardiology
Răchitoasa, Romania
Emergency Institute For Cardiovascular Diseases And Transplant
Cardiology
Sângeorgiu de Mureş, Romania
Spitalul Clinic Judetean De Urgenta Targu Mures
Cardiology
Sângeorgiu de Mureş, Romania
Spital Judetean De Urgenta Satu Mare
Cardiology
Satu Mare, Romania
Cardio Med S.R.L.
Cardiology
Târgu Mureş, Romania
CMI Dr. Podoleanu Cristian
Cardiology
Târgu Mureş, Romania
Cabinet Medical Dr Tudoran S.R.L.
Cardiology
Timişoara, Romania
Institutul De Boli Cardiovasculare Timisoara
Cardiology
Timişoara, Romania
Institutul De Boli Cardiovasculare Timisoara
Cardiology
Timişoara, Romania
Medicali's S.R.L.
Cardiology
Timişoara, Romania
Sal Med S.R.L.
Cardiology
Timişoara, Romania
Spitalul Clinic Municipal De Urgenta Timisoara
Cardiology
Timişoara, Romania
Alian s.r.o.
Cardiology
Bardejov, Slovakia
Nemocnica S Poliklinikou Prievidza So Sidlom V Bojniciach
Department of internal medicine
Bojnice, Slovakia
Medical group Kosice s.r.o.
Cardiology
Košice, Slovakia
Kardio 1
Cardiology
Lučenec, Slovakia
Cardioamb s.r.o.
Cardiology
Nové Zámky, Slovakia
Benimed s.r.o.
Cardiology
Piešťany, Slovakia
Galenum s.r.o.
Cardiology
Vrakuňa, Slovakia
Medivasa s.r.o.
Cardiology
Žilina, Slovakia
Complejo Universitario Juan Canalejo
Cardiology department
A Coruña, Spain
Hospital Universitario Torrecardenas
Cardiology department
Almería, Spain
Hospital Universitari Vall D Hebron
Hematology
Barcelona, Spain
Centro De Salud Cabra Matrona Antonia Mesa Fernandez
Cardiology department
Cabra, Spain
Hospital Universitario La Paz
Cardiology department
Chamartín, Spain
Hospital Universitario Puerta De Hierro De Majadahonda
Cardiology department
Chamartín, Spain
Hospital De La Santa Creu I Sant Pau
Haematolgyk
Fraga, Spain
University Clinical Hospital Virgen De La Arrixaca
Cardiology department
Fuente-Álamo de Murcia, Spain
Hospital Universitario Virgen De Las Nieves
Cardiology department
Granada, Spain
University Hospital Virgen Del Rocio S.L.
Respiratory department
Huelva, Spain
Hospital Universitario De Jaen
Cardiology department
Jaén, Spain
Bellvitge University Hospital
Cardiology
L'Hospitalet de Llobregat, Spain
Hospital Universitario De Leon
Neurología
León, Spain
Hospital La Luz Grupo Quironsalud
Cardiology department
Madrid, Spain
Hospital La Luz Grupo Quironsalud
Cardiology
Madrid, Spain
Hospital La Milagrosa S.A.
Cardiology department
Madrid, Spain
Hospital Universitario Virgen De La Victoria
Cardiology department
Málaga, Spain
Hospital Universitario Central De Asturias
Cardiology
Oviedo, Spain
Hospital Universitario Central De Asturias
Cardiology department
Oviedo, Spain
Parc Tauli Hospital Universitari
Cardiology
Sabadell, Spain
Complexo Hospitalario Universitario De Santiago
Cardiology department
Santiago de Compostela, Spain
Hospital Universitario Virgen De La Macarena
Cardiology department
Sevilla, Spain
Hospital Clinico Universitario De Valencia
Cardiology department
Valencia, Spain
Complexo Hospitalario Universitario De Vigo
Cardiology department
Vigo, Spain
Fundacio Assistencial De Mutua De Terrassa
Cardiology department
Vilanova i la Geltrú, Spain
Danderyds Sjukhus AB
Hjärtkliniken, Danderyds Sjukhus AB Entrevaegen 2, Danderyd 18288 Stockholm SWEDEN
Bergshamra, Sweden
Region Oerebro Laen
Örebro University hospital, Department of Cardiology, 701 85 Örebro, Sweden
Örebro, Sweden
Akardo AB
Cardiology
Stockholm, Sweden
Sponsor: Anthos Therapeutics Inc.
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.