B-Cell Acute Lymphoblastic Leukemia: AZD0486 Study

We are investigating whether AZD0486 is safe and effective for adolescents and adults with relapsed or refractory B-cell acute lymphoblastic leukemia. This trial aims to understand how well it works compared to existing treatments.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Suvartar

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Tocilizumab
Tocilizumab is a substance that reduces harmful inflammation by targeting the immune system to treat autoimmune conditions such as rheumatoid arthritis.
Valsartan
Valsartan is a substance that helps lower high blood pressure and reduces strain on the heart.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Azd0486
Monoclonal Antibody

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Almertan
Alsartir
Amlodipin/Valsartan/Hydrochlorothiazid Ratiopharm

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire De Caen Normandie
IHBN
Caen, France
Robert Debre University Hospital
Service d'hemato-immunologie
Le Pré-Saint-Gervais, France
Institut Paoli-Calmettes
Pôle Hématologie
Marseille, France

Sponsor: Astrazeneca AB
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.