B-cell Acute Lymphoblastic Leukemia: UCART22 Treatment Study

We are testing a new engineered T-cell therapy, UCART22, for patients with relapsed or refractory B-ALL. The study aims to evaluate its safety and effectiveness, especially for those who have not responded to other therapies.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Endoxan
Endoxan is a chemotherapy medicine used to treat various types of cancer and some severe autoimmune conditions.
Fludara
Fludara is a chemotherapy medicine used to treat certain blood cancers, especially chronic lymphocytic leukemia.
Lemtrada
Lemtrada is a medicine used to treat relapsing forms of multiple sclerosis, helping reduce attacks and slow disease progression.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Achillea Millefolium Seed
Achillea millefolium seed is a plant-derived substance traditionally used to help soothe minor skin irritation and support wound healing.
Alemtuzumab
Alemtuzumab is a lab-made antibody that targets immune cells and treats certain blood cancers and severe relapsing multiple sclerosis.
Capparis Spinosa Cortex
Capparis spinosa cortex is a plant-derived substance traditionally used to support liver function and ease digestive complaints.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Ucart22

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Bendarabin
Beneflur
Blitzima

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Centre Hospitalier Universitaire De Bordeaux
Service d'hématologie clinique et de thérapie cellulaire
Canéjan, France
Assistance Publique Hopitaux De Paris
Pediatric Hematology-Immunology Department
Le Pré-Saint-Gervais, France
Centre Hospitalier Universitaire De Nantes
Hématologie
Nantes, France

Sponsor: Cellectis
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.