B-Cell Malignancies: BGB-16673 Treatment Study

We are investigating the safety and effectiveness of BGB-16673 combined with other treatments for patients with relapsed or refractory B-cell malignancies. This study aims to find the best dose and assess how well the treatment works.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Columvi
Columvi is a cancer medicine used to treat certain B‑cell lymphomas, a type of blood cancer, when other treatments have failed.
Gazyvaro
Gazyvaro is a cancer medicine used to treat certain blood cancers, including some types of lymphoma and chronic lymphocytic leukemia.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Glofitamab
Glofitamab is a lab-made antibody that helps the immune system target and kill abnormal B cells in certain types of B-cell lymphoma.
Mosunetuzumab
Mosunetuzumab is a lab-made antibody that helps the immune system target and kill certain B-cell lymphomas.
Obinutuzumab
Obinutuzumab is a lab-made antibody that targets and helps eliminate B cells to treat certain blood cancers like chronic lymphocytic and follicular lymphoma.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Bgb-16673
Bgb-11417
N-[4-({[(1R,4R)-4-Hydroxy-4-Methylcyclohexyl]Methyl}Amino)-3-Nitrobenzene-1-Sulfonyl]-4-(2-{(2S)-2-[2-(Propan-2-yl)Phenyl]Pyrrolidin-1-yl}-7-Azaspiro[3.5]Nonan-7-yl)-2-[(1H-Pyrrolo[2,3-b]Pyridin-5-yl)Oxy]Benzamide

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Technische Universitaet Dresden
Medizinische Klinik und Poliklinik I
Dresden, Germany
Universitaetsklinikum Jena KöR
Hämatologie und internistische Onkologie
Jena, Germany
Universitaetsklinikum Schleswig-Holstein AöR
Medical Department II
Kiel, Germany

Sponsor: BeOne Medicines AG
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.