Bladder Cancer: V940 and BCG Combination Study

We are investigating whether a new treatment, V940, combined with BCG can improve outcomes for people with high-risk non-muscle invasive bladder cancer compared to BCG alone. This study will also assess the safety of all treatment options.

>2 years Efficacy phase (II)No Placebo Partially Remote Investigational Medicines InjectionOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Bcg Vaccine Ajv

Bcg Vaccine Ajv is a vaccine used to help prevent severe forms of tuberculosis, especially in infants and young children.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Bacillus Calmette-Guérin (Bcg)

Bacillus Calmette-Guérin (BCG) is a vaccine that helps protect against severe forms of tuberculosis, especially in young children.

Danish Strain 1331

Mycobacterium Bovis

Mycobacterium bovis is a bacterium used in vaccines to prevent tuberculosis and to stimulate the immune system against some bladder cancers.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Mrna-4157

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Bcg Szczepionka Ajvaccines

Bcg Vaccin Ajv

Bcg Vaccine "aj Vaccines"

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...

Odense University Hospital

Department of Urology

Odense, Denmark

Region Hovedstaden

Urinvejssygdomme

Rødovre, Denmark

Centre Hospitalier Universitaire De Bordeaux

Urology

Bordeaux, France

Sponsor: Merck Sharp & Dohme LLC

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.