BOTOX for Masseter Muscle Prominence

We are studying whether BOTOX injections can help reduce the prominence of the masseter muscle in adults. This trial compares BOTOX to a placebo to evaluate its effectiveness and safety.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Botox
Botox is a medicine used to relax muscles to reduce facial wrinkles and treat certain muscle- and nerve-related conditions.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Botulinum Antitoxin Type A Ph. Eur.
Botulinum antitoxin type A is a substance that neutralizes botulinum toxin to treat and prevent worsening paralysis caused by botulism.
Botulinum Toxin Type A
Botulinum toxin type A is a substance that temporarily relaxes muscles to reduce wrinkles and treat muscle overactivity.
Botulinum Toxin Type A - Haemagglutinin Complex
Botulinum toxin type A with haemagglutinin complex temporarily relaxes muscles by blocking nerve signals to treat muscle spasms and reduce wrinkles.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alluzience
Azzalure
Dysline

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Dermatologie Kempenland
Davinciclinic
Beerse, Belgium
UZ Brussel
Dermatology
Ganshoren, Belgium
Aesthics
Lightfalls Clinic
Melle, Belgium

Sponsor: Abbvie Deutschland GmbH & Co. KG
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.