Hot Flashes
Hot flashes are sudden feelings of warmth, often accompanied by sweating and discomfort, commonly experienced during menopause or due to hormonal changes.
Breast Cancer: Fezolinetant for Hot Flashes
We are studying whether fezolinetant can help reduce hot flashes in women with hormone receptor-positive breast cancer receiving hormone therapy. The trial also looks at how this treatment affects quality of life and sleep.
1-2 years11-15 visitsConfirmation phase (III)Partially RemoteStandard MedicinesOralEndocrinologyOncology
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you a woman aged 18 or older?
- Do you have a history of breast cancer that is stage 0 to 3?
- Are you currently taking medications for breast cancer, like tamoxifen or anastrozole?
- Have you had any surgery or treatment for breast cancer in the last 3 months?
- Do you have any serious kidney problems, like a creatinine level above 1.5?
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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GYN Mika s.r.o.
České Budějovice, Czechia
NH Hospital a.s.
Onkologický stacionář
Hořovice, Czechia
Fakultni Nemocnice Hradec Kralove
Klinika onkologie a radioterapie
Hradec Králové, Czechia
Sponsor: Astellas Pharma Global Development Inc.
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.