Breast Cancer: Inavolisib Treatment Study

We are testing a new treatment using Inavolisib for patients with early-stage, PIK3CA-mutated breast cancer. The study aims to evaluate how safe and effective this treatment is for participants.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Kisqali
Kisqali is a medicine used to treat certain types of advanced or metastatic breast cancer by slowing cancer cell growth.
Letrozole
Letrozole is a medicine used to treat certain breast cancers in women after menopause by lowering hormones that can fuel tumor growth.
Letrozole Accord Healthcare
Letrozole Accord Healthcare is a medicine used to treat certain types of breast cancer in postmenopausal women.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Letrozole
Letrozole is a substance that lowers estrogen to treat certain types of breast cancer in postmenopausal women.
Ribociclib
Ribociclib is a substance that slows growth of certain breast cancers by blocking proteins that help cancer cells divide.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Inavolisib

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aletro
Aletro
Allenda

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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HELIOS Klinikum Berlin-Buch GmbH
Klinik für Geburtshilfe und Gynäkologie
Bernau bei Berlin, Germany
Technische Universitaet Dresden
Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe
Dresden, Germany
KEM I Evang. Kliniken Essen-Mitte gGmbH
Klinik für Senologie/Brustzentrum
Essen, Germany

Sponsor: F. Hoffmann-La Roche AG
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.