Breast Cancer Prevention: Exemestane vs. Tamoxifen

We are comparing two low-dose medications for post-menopausal women at high risk for breast cancer to see which one may improve quality of life and hormonal balance. This study aims to understand their effects over 12 months.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Exemestane
Exemestane is a medicine used to lower estrogen and treat certain breast cancers in women who have gone through menopause.
Tamoxifen
Tamoxifen is a medicine used to treat and help prevent certain types of breast cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Exemestane
Exemestane is a substance that lowers estrogen levels to help treat hormone-sensitive breast cancer in postmenopausal women.
Tamoxifen
Tamoxifen is a substance that blocks estrogen effects to treat and help prevent certain breast cancers that respond to estrogen.
Tamoxifen Citrate
Tamoxifen citrate is a substance that blocks estrogen's effects to treat and help prevent certain types of breast cancer.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Adifen 10mg
Aromaplex
Aromasil

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Ente Ospedaliero Ospedali Galliera Di Genova
S.C. Oncologia Medica
Genoa, Italy
Istituto Europeo Di Oncologia S.r.l.
Prevenzione e Genetica Oncologica
Opera, Italy
Sponsor: Ente Ospedaliero Ospedali Galliera Di Genova
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.