Metastatic Breast Cancer
Metastatic breast cancer occurs when breast cancer cells spread to other parts of the body, such as the bones, liver, or lungs. This advanced stage of cancer can lead to various symptoms and requires specialized treatment.
Breast Cancer: Trastuzumab-Deruxtecan Treatment Study
We are investigating if switching to a new drug can help patients with HR+ HER2 low metastatic breast cancer who are not responding well to standard therapy. This study aims to find out if this change improves survival and response rates.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you at least 18 years old?
- Are you currently pregnant, breastfeeding, or planning to become pregnant?
- Do you have breast cancer that has spread to other parts of your body?
- Are you taking any medications that could interact with the study drugs, such as strong CYP3A4 inhibitors like Ketoconazole or Clarithromycin?
- Have you had any major surgery in the last 4 weeks?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Ds-8201a
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Clinique De L'Europe
Medical oncology
Amiens, France
Centre Hospitalier D Auxerre
Medical oncology
Auxerre, France
Sainte Catherine Institut Du Cancer Avignon-Provence
Medical oncology
Avignon, France
Sponsor: Unicancer
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.